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E621Flavor enhancerLow concern

Monosodium Glutamate

In plain words

The short version

A sodium salt of glutamic acid used to deepen savory (umami) flavor in foods.

Why it's green

A flavour enhancer that adds a savoury 'umami' taste. Most people tolerate it fine and the old 'Chinese-restaurant syndrome' scare was never confirmed, but a minority report short-lived headaches or flushing after large amounts. That's why we flag it mildly.

01Origin

Where it comes from

Isolated in 1908 by Kikunae Ikeda from kombu seaweed, who named the taste 'umami'. Originally extracted from wheat gluten; today produced by bacterial fermentation of sugar cane molasses.

02Usage

How it's used

Used in soups, sauces, snack foods, processed meats, and Asian cuisine. Typical use 0.1% to 0.8% by weight.

03Safety

Safety profile

No ADI specified by JECFA. The 'Chinese Restaurant Syndrome' reported in the 1960s has not been confirmed in controlled double-blind studies. Glutamate is the most abundant amino acid in the human diet and an essential neurotransmitter. Rare individuals report sensitivity at high doses.

04Properties

Physical & chemical properties

White crystalline powder, very soluble in water. Dissociates to free glutamate, which activates umami receptors on the tongue.

05Regulation

Regulation worldwide

Permitted globally. EU labeling requires clear identification.

Educational information only. Not medical or dietary advice.