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E466ThickenerModerate concern

Carboxymethyl Cellulose

In plain words

The short version

A modified cellulose gum used to thicken, stabilize, and add texture in many processed foods.

Why we flag it amber

It's permitted and generally considered safe, but there are a few reasons to be mindful — like sensitivities in some people, debated studies, or intake limits. The Safety section below explains the specifics.

Safety

Safety profile

No ADI specified by JECFA. Recent animal and human studies have raised concerns that some emulsifiers, including CMC, may alter the gut microbiome and promote low-grade inflammation. Evidence in humans is still emerging.

The detail

Educational information only. Not medical or dietary advice.