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E218PreservativeModerate concern

Methyl p-Hydroxybenzoate

In plain words

The short version

A methyl paraben preservative — historically the most common paraben, now restricted in EU food use.

Why we flag it amber

It's permitted and generally considered safe, but there are a few reasons to be mindful — like sensitivities in some people, debated studies, or intake limits. The Safety section below explains the specifics.

Safety

Safety profile

ADI of 10 mg/kg body weight (combined methyl, ethyl, and their salts). Weak estrogenic activity reported in vitro; the relevance at food-additive levels is debated. Some studies have found parabens in human breast tissue, which raised public concern but is not in itself evidence of harm.

The detail

Sources

  1. WHO JECFA database — Methyl p-hydroxybenzoate (INS 218), group ADI 0–10 mg/kg bw (1973; propylparaben excluded 2006) — WHO / Joint FAO/WHO Expert Committee on Food Additives, 1973. Group ADI 0–10 mg/kg bw for methyl + ethyl esters
  2. EFSA — 'EFSA advises on the safety of paraben usage in food' (news on the AFC Panel opinion on E 214-219, 29 September 2004) — European Food Safety Authority, 2004. EFSA 2004 group ADI 0–10 mg/kg bw for methyl and ethyl parabens and their sodium salts
  3. EUR-Lex — Regulation (EC) No 1333/2008 on food additives, consolidated text of 18 August 2026 (Annex II) — European Union (Publications Office), 2026. EU: permitted only in restricted food categories
  4. eCFR — 21 CFR 184.1490 Methylparaben (GRAS) — U.S. Food and Drug Administration / Office of the Federal Register, 1984. US: GRAS antimicrobial, GMP maximum 0.1% in food

Checked against these sources on .

Educational information only. Not medical, dietary or veterinary advice. Spotted an error? Tell us.