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E143ColorantModerate concern

Fast Green FCF

In plain words

The short version

A US-approved synthetic green triarylmethane dye — not approved in the EU.

Why we flag it amber

It's permitted and generally considered safe, but there are a few reasons to be mindful — like sensitivities in some people, debated studies, or intake limits. The Safety section below explains the specifics.

Safety

Safety profile

ADI of 0–25 mg/kg body weight (JECFA, confirmed in 2017). Not in the Southampton six trial. Some early bladder-tumor concerns from rat studies have not been reproduced in modern toxicology. Limited absorption (~5% in humans) — most is excreted unchanged in feces.

The detail

Sources

  1. WHO JECFA database — Fast Green FCF (INS 143), 84th meeting 2017 — World Health Organization / JECFA, 2017. safety: ADI 0–25 mg/kg bw
  2. US eCFR — 21 CFR 74.203 FD&C Green No. 3 — U.S. Government Publishing Office / Office of the Federal Register (eCFR), 2026. regulation: permitted in US foods
  3. FDA — HHS, FDA to Phase Out Petroleum-Based Synthetic Dyes in Nation's Food Supply (22 April 2025) — U.S. Food and Drug Administration, 2025. regulation: US plan to phase out Green No. 3 with industry

Checked against these sources on .

Educational information only. Not medical, dietary or veterinary advice. Spotted an error? Tell us.