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E252PreservativeModerate concern

Potassium Nitrate

In plain words

The short version

Saltpeter — a slow-release curing agent that converts to nitrite during meat ageing.

Why we flag it amber

A traditional curing salt that converts to nitrite in the meat, protecting against botulism but able to form nitrosamines — compounds linked to cancer. That trade-off is why we flag it.

Safety

Safety profile

ADI of 0–3.7 mg/kg body weight. Lower direct toxicity than nitrite but converts to nitrite in storage and digestion, where the same N-nitrosamine concerns apply. The combined nitrite + nitrate dietary load (including from vegetables) drives the risk profile.

The detail

Sources

  1. WHO JECFA database: Potassium nitrate (INS 252), ADI 0–3.7 mg/kg bw as nitrate ion — World Health Organization / JECFA, 1995. ADI of 0–3.7 mg/kg bw
  2. EFSA: Re-evaluation of sodium nitrate (E 251) and potassium nitrate (E 252) as food additives, EFSA Journal 2017;15(6):4787 — European Food Safety Authority, 2017. ADI 3.7 mg/kg bw/day maintained; total dietary nitrate drives exceedance
  3. EUR-Lex: Commission Regulation (EU) 2023/2108 amending Annex II to Regulation (EC) No 1333/2008 as regards nitrites (E 249–250) and nitrates (E 251–252) — European Union (EUR-Lex), 2023. Lowered EU maximum added amounts for nitrates in meat (from 9 Oct 2025) and cheese (from 9 Oct 2026)
  4. eCFR: 21 CFR 181.33 Sodium nitrate and potassium nitrate (prior sanctions), current text — U.S. Government (eCFR, Office of the Federal Register), 2026. US status as a curing agent for meat and poultry

Checked against these sources on .

Educational information only. Not medical, dietary or veterinary advice. Spotted an error? Tell us.